The structural consequences of newly diagnosed seizures.

  title={The structural consequences of newly diagnosed seizures.},
  author={Rebecca S. N. Liu and Louis Lemieux and Gail S. Bell and Sanjay M. Sisodiya and Philippa A. Bartlett and Simon D. Shorvon and Josemir W. Sander and John S. Duncan},
  journal={Annals of neurology},
  volume={52 5},
Intractable epilepsy may be associated with widespread structural cerebral damage. We determined whether structural damage occurs to the hippocampus, cerebellum and neocortex in the first few years following a diagnosis of seizures. Sixty-eight patients over the age of 14 years with newly diagnosed seizures and 90 matched controls underwent serial magnetic resonance imaging (MRI) brain scans 3.5 years apart. Using quantitative analysis of serial scans, we determined changes in hippocampal… CONTINUE READING
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