The structural basis of calcium transport by the calcium pump

@article{Olesen2007TheSB,
  title={The structural basis of calcium transport by the calcium pump},
  author={Claus Olesen and Martin Picard and Anne-Marie Lund Winther and Claus Gyrup and Jens Preben Morth and Claus Oxvig and Jesper Vuust M{\o}ller and Poul Nissen},
  journal={Nature},
  year={2007},
  volume={450},
  pages={1036-1042}
}
The sarcoplasmic reticulum Ca2+-ATPase, a P-type ATPase, has a critical role in muscle function and metabolism. Here we present functional studies and three new crystal structures of the rabbit skeletal muscle Ca2+-ATPase, representing the phosphoenzyme intermediates associated with Ca2+ binding, Ca2+ translocation and dephosphorylation, that are based on complexes with a functional ATP analogue, beryllium fluoride and aluminium fluoride, respectively. The structures complete the cycle of… 
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TLDR
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