• DOI:10.1007/BF02462474
• Corpus ID: 9132976

The structural bases of the regulation of neuron sensitivity

@article{Babmindra2006TheSB,
  title={The structural bases of the regulation of neuron sensitivity},
  author={V. P. Babmindra and A. P. Novozhilova and T. A. Bragina and G. S. Kreichman and O. E. Myasnikova and Nadezhda T Zhilinskaya and G. V. Kolla},
  journal={Neuroscience and Behavioral Physiology},
  year={2006},
  volume={29},
  pages={615-620}
}

• V. P. Babmindra, A. P. Novozhilova, +4 authors G. V. Kolla
• Published 1 November 1999
• Biology
• Neuroscience and Behavioral Physiology

The sensitivity of neurons and their ability to perceive synaptic spikes are not constant and change, depending on a number of factors; one important factor is the structure of interneuronal synapses. The efficiency of synapse operation, which is characterized by the amplitude of the excitatory postsynaptic potential, is determined by number and qualitative composition of synaptic vesicles, the size of the presynapses, the area of the active zone, the curvature of the plasma membrane, and the specific structure of the postsynaptic density. Changes in the structure of any of these components is unavoidably reflected in synaptic efficiency. Thus, data on the ultrastructure of synaptic contacts in changing conditions are very important for understanding synaptic efficiency. Since neurophysiology still lacks methods for studying the functions of the ultrastructural components of synapses, neuromorphology plays an important role in addressing this question. The aim of the present work was to compare our own morphological data on synapse structure with published data on their functions.