The stringent response in Myxococcus xanthus is regulated by SocE and the CsgA C-signaling protein.

@article{Crawford2000TheSR,
  title={The stringent response in Myxococcus xanthus is regulated by SocE and the CsgA C-signaling protein.},
  author={Eric W. Crawford and Lawrence Joseph Shimkets},
  journal={Genes & development},
  year={2000},
  volume={14 4},
  pages={483-92}
}
Myxococcus xanthus fruiting body development is induced by amino acid limitation. The decision to grow or develop is established by the RelA-dependent stringent response and A-signaling. We identified two new members of this regulatory hierarchy, socE and the C-signaling gene csgA. SocE depletion arrests growth and induces sporulation under conditions that normally favor growth as well as curtailing DNA and stable RNA synthesis, inhibiting cell elongation, and inducing accumulations of the… CONTINUE READING

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