The stress response to surgical trauma: from physiological basis to therapeutic implications.

@article{Anand1986TheSR,
  title={The stress response to surgical trauma: from physiological basis to therapeutic implications.},
  author={Kanwaljeet J S Anand},
  journal={Progress in food & nutrition science},
  year={1986},
  volume={10 1-2},
  pages={
          67-132
        }
}
The response to surgical injury is mediated through the hypothalamus and is characterised by the release of catecholamines, glucocorticoids, growth hormone and glucagon; the suppression of insulin secretion and changes in other endocrine systems. These hormonal responses trigger a cascade of metabolic adjustments leading to catabolism and substrate mobilization in the postoperative period. There is evidence that a severe and prolonged catabolic reaction to injury may be associated with an… CONTINUE READING

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