The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune response.

Abstract

The mammalian intestine is colonized by a dense microbial community, the microbiota. Homeostatic and symbiotic interactions facilitate the peaceful co-existence between the microbiota and the host, and inhibit colonization by most incoming pathogens ('colonization resistance'). However, if pathogenic intruders overcome colonization resistance, a fierce… (More)
DOI: 10.1111/j.1600-065X.2011.01070.x

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Cite this paper

@article{Kaiser2012TheSM, title={The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune response.}, author={Patrick O Kaiser and M{\'e}d{\'e}ric Diard and B{\"a}rbel Stecher and Wolf-Dietrich Hardt}, journal={Immunological reviews}, year={2012}, volume={245 1}, pages={56-83} }