The strange case of the signal recognition particle

  • Karl S Matlin
  • Published 2002 in Nature Reviews Molecular Cell Biology


The discovery of the signal-recognition particle (SRP) and its receptor represented a huge step forwards in the study of protein translocation and secretion. Just as intriguing was the race to identify SRP, as two teams — one based in New York, the other in Heidelberg — took up the quest and scored complementary victories. 
DOI: 10.1038/nrm857

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