The stochastic digital human is now enrolling for in silico imaging trials - Methods and tools for generating digital cohorts

  title={The stochastic digital human is now enrolling for in silico imaging trials - Methods and tools for generating digital cohorts},
  author={Aldo Badano and Miguel A. Lago and Elena Sizikova and JG Delfino and Song Guan and Mark A. Anastasio and Berkman Sahiner},
. Randomized clinical trials, while often viewed as the highest evidentiary bar by which to judge the quality of a medical intervention, are far from perfect. In silico imaging trials are computational studies that seek to ascertain the performance of a medical device by collecting this information entirely via computer simulations. The benefits of in silico trials for evaluating new technology include significant resource and time savings, minimization of subject risk, the ability to study… 

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