The stimulatory effect of PDGF on vascular smooth muscle cell migration is mediated by the induction of endogenous basic FGF.

@article{Sato1991TheSE,
  title={The stimulatory effect of PDGF on vascular smooth muscle cell migration is mediated by the induction of endogenous basic FGF.},
  author={Yoichi Sato and Robert B Hamanaka and Junko Ono and Michihiko Kuwano and Daniel B. Rifkin and Ryosaburo Takaki},
  journal={Biochemical and biophysical research communications},
  year={1991},
  volume={174 3},
  pages={1260-6}
}
The migration of arterial smooth muscle cells from the media to the intima is a crucial event for the development of the atherosclerotic lesion, and platelet derived growth factor (PDGF) is thought to play an important role in this process. Here we report that the spontaneous migration of bovine smooth muscle (BSM) cells is dependent on endogenously produced basic fibroblast growth factor (bFGF). PDGF stimulates the migration of BSM cells and its effect is abolished by affinity purified anti… CONTINUE READING

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