The stimulation of healing within a rat calvarial defect by mPCL-TCP/collagen scaffolds loaded with rhBMP-2.

@article{Sawyer2009TheSO,
  title={The stimulation of healing within a rat calvarial defect by mPCL-TCP/collagen scaffolds loaded with rhBMP-2.},
  author={Amber A Sawyer and Su Jin Song and Evelyn Susanto and Peiying Chuan and Christopher Xu Fu Lam and Maria A. Woodruff and Dietmar Werner Hutmacher and Simon M Cool},
  journal={Biomaterials},
  year={2009},
  volume={30 13},
  pages={2479-88}
}
Bone morphogenetic proteins (BMPs) have been widely investigated for their clinical use in bone repair and it is known that a suitable carrier matrix to deliver them is essential for optimal bone regeneration within a specific defect site. Fused deposited modeling (FDM) allows for the fabrication of medical grade poly epsilon-caprolactone/tricalcium phosphate (mPCL-TCP) scaffolds with high reproducibility and tailor designed dimensions. Here we loaded FDM fabricated mPCL-TCP/collagen scaffolds… CONTINUE READING
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In vitro bone engineering based on polycaprolactone–tricalcium phosphate composites

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