The stimulation of bone formation in vitro by therapeutic ultrasound.

@article{Reher1997TheSO,
  title={The stimulation of bone formation in vitro by therapeutic ultrasound.},
  author={P Reher and Elbeshir el-NI and William Harvey and Sajeda Meghji and Malcolm Harris},
  journal={Ultrasound in medicine & biology},
  year={1997},
  volume={23 8},
  pages={1251-8}
}
A controlled study was performed to evaluate the effects of different ultrasound (US) intensities on 5-day-old mouse calvaria bone in tissue culture. A special technique to apply the US was developed, and the following parameters were measured: collagen and noncollagenous protein (NCP) synthesis (bone formation), and temperature change. It was found that ultrasound at 0.1 W/cm2 (SATA), pulsed 1:4, 3 MHz, 5 min, significantly stimulates bone formation (i.e., the synthesis of collagen and NCP) (p… CONTINUE READING