The stepwise biphotonic photoionization of chlorpromazine as seen by laser flash photolysis.

  title={The stepwise biphotonic photoionization of chlorpromazine as seen by laser flash photolysis.},
  author={Garry R Buettner and R D Hall and Colin F. Chignell and Ann G Motten},
  journal={Photochemistry and photobiology},
  volume={49 3},
It is generally accepted that both promazine (PZ) and chlorpromazine (CPZ) photionize monophotonically to their respective cation radicals and the corresponding hydrated electrons. It is also supposed that this photoinization has a role in the phototoxic effects of these drugs. However, using laser flash photolysis, we have observed that photoionization of CPZ during S1 excitation (lambda greater than 300 nm) is a stepwise biphotonic process. In the case of PZ our flash photolysis results are… CONTINUE READING


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