The steps that lead to the formation of a single primitive heart tube are highly conserved in vertebrate and invertebrate embryos. Concerted migration of the two lateral cardiogenic regions of the mesoderm and endoderm


Cell interactions between the extracellular matrix (ECM) and neighboring cells play crucial roles in the regulation of cell behavior and fate. From the very first stages of embryogenesis, these interactions are a prerequisite for the full expression of the determination-differentiation properties of cells and for tissue organization. Beyond the obvious… (More)


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