The stem cell marker nestin predicts poor prognosis in human melanoma.

Abstract

The cancer stem cell hypothesis suggests that mutated melanocyte stem cells are present in skin as precursors of melanoma cells. Nestin and CD133 have been described as markers of melanocytic stem cells. The aim of this study was to establish if melanocytic stem cells could have a prognostic significance in melanoma progression. An immunohistochemical study… (More)

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@article{Piras2010TheSC, title={The stem cell marker nestin predicts poor prognosis in human melanoma.}, author={Franca Piras and Maria Teresa Perra and Daniela Murtas and Luigi Minerba and Carlo Aurelio Floris and Cristina Maxia and Paolo Demurtas and J M Ugalde and Domenico Ribatti and Paola Sirigu}, journal={Oncology reports}, year={2010}, volume={23 1}, pages={17-24} }