The status of olfactory function and the striatal dopaminergic system in drug-induced parkinsonism

@article{Bovi2010TheSO,
  title={The status of olfactory function and the striatal dopaminergic system in drug-induced parkinsonism},
  author={Tommaso Bovi and Angelo Antonini and Sarah Ottaviani and Angela Antonioli and Maria Paola Cecchini and Vincenzo Di Francesco and Maria Antonietta Bassetto and Mauro Zamboni and Antonio Fiaschi and Giuseppe Moretto and Andrea Sbarbati and Michele Tinazzi and Francesco Osculati},
  journal={Journal of Neurology},
  year={2010},
  volume={257},
  pages={1882-1889}
}
Olfactory impairment has been reported in drug-induced parkinsonism (DIP), but the relationship between dopaminergic dysfunction and smell deficits in DIP patients has not been characterized. To this end, we studied 16 DIP patients and 13 patients affected by Parkinson’s disease (PD) using the “Sniffin’ Sticks” test and [123I] FP-CIT SPECT (single-photon emission computed tomography). DIP patients were divided based on normal (n = 9) and abnormal (n = 7) putamen dopamine transporter binding… CONTINUE READING

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In this group of patients , olfactory TDI scores ( odor threshold , discrimination and identification ) correlated significantly with putamen uptake values , as observed in PD patients .
In this group of patients , olfactory TDI scores ( odor threshold , discrimination and identification ) correlated significantly with putamen uptake values , as observed in PD patients .
In this group of patients , olfactory TDI scores ( odor threshold , discrimination and identification ) correlated significantly with putamen uptake values , as observed in PD patients .
In this group of patients , olfactory TDI scores ( odor threshold , discrimination and identification ) correlated significantly with putamen uptake values , as observed in PD patients .
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