The state of vaccine safety science: systematic reviews of the evidence.

  title={The state of vaccine safety science: systematic reviews of the evidence.},
  author={Matthew Z. Dudley and Neal A. Halsey and Saad B. Omer and Walter A. Orenstein and Sean T O'Leary and Rupali J. Limaye and Daniel A. Salmon},
  journal={The Lancet. Infectious diseases},

Immunization practices and risk of anaphylaxis: a current update, comprehensive of COVID-19 vaccination data

An updated report on the correlation between vaccines and anaphylaxis and the related risk in the population is provided and every suspected contraindication has to be deepened to maximize effectiveness and safety profile.

Safety of Immunizations for the Adult Patient With Inflammatory Bowel Disease-A Systematic Review and Meta-analysis.

This study demonstrated that AEs after vaccination are mainly local or mildly systemic and do not differ significantly from the expected AE after recommended immunizations for the general population, and gastroenterologists should reinforce that vaccines are safe in patients with IBD.

Aseptic Meningitis Following Second Dose of an mRNA Coronavirus Disease 2019 Vaccine in a Healthy Male: Case Report and Literature Review

A 32-year-old healthy man visited the authors' hospital with a complaint of headache and suspected aseptic meningitis associated with the vaccination and intravenous methylprednisolone was administered for 3 days, the symptoms improved and the patient was discharged on day 12 of hospitalization.

Vaccination in pediatric acquired inflammatory immune-mediated neuromuscular disorders.

COVID-19 Vaccine in Pregnant and Lactating Women: A Review of Existing Evidence and Practice Guidelines

The available data on the efficacy and safety profile of COVID-19 vaccination in pregnant and lactating women are summarized, the challenges of vaccine hesitancy are reviewed, and recommendations for healthcare providers are included.

An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times

In the present review, some aspects involved in accomplishing a successful vaccination program are addressed, in addition to the importance of vaccination in a pandemic in the face of unwillingness, conspiracy theories, or a lack of information among the public.

Immunosuppression and immunization: Vaccination in pediatric patients with neuromuscular diseases treated with steroids or immune-modulating drugs.



Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Causality

This volume provides the most thorough literature review available about links between common childhood vaccines--tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis B--and specific types of disorders or death.

Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review

Evidence that some vaccines are associated with serious AEs is found; however, these events are extremely rare and must be weighed against the protective benefits that vaccines provide.

Immunization Safety Review: Multiple Immunizations and Immune Dysfunction

The Immunization Safety Review Committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction and found that the epidemiological evidence favors rejection of a causal relationship between multiple immunization and increased risk for infections and for type 1 diabetes.

Safety of Vaccines Used for Routine Immunization in the United States.

Evidence was insufficient to make conclusions regarding whether several routinely recommended vaccines are associated with serious conditions such as multiple sclerosis, transverse myelitis, and acute disseminated encephalomyelitis; however, important factors must be taken into account when determining whether studies are warranted.

Adverse Effects of Vaccines

While no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines, and the evidence shows that vaccines do not cause several conditions.

Vaccine administration and the development of immune thrombocytopenic purpura in children

The available data clearly indicate that ITP is very rare and the only vaccine for which there is a demonstrated cause-effect relationship is the measles, mumps and rubella vaccine that can occur in 1 to 3 children every 100,000 vaccine doses.