The state of vaccine safety science: systematic reviews of the evidence.

@article{Dudley2020TheSO,
  title={The state of vaccine safety science: systematic reviews of the evidence.},
  author={Matthew Z. Dudley and Neal A. Halsey and Saad B. Omer and Walter A. Orenstein and Sean T O'Leary and Rupali J. Limaye and Daniel A. Salmon},
  journal={The Lancet. Infectious diseases},
  year={2020}
}

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The available data on the efficacy and safety profile of COVID-19 vaccination in pregnant and lactating women are summarized, the challenges of vaccine hesitancy are reviewed, and recommendations for healthcare providers are included.

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References

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This volume provides the most thorough literature review available about links between common childhood vaccines--tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis B--and specific types of disorders or death.

Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review

Evidence that some vaccines are associated with serious AEs is found; however, these events are extremely rare and must be weighed against the protective benefits that vaccines provide.

Immunization Safety Review: Multiple Immunizations and Immune Dysfunction

The Immunization Safety Review Committee reviewed the evidence regarding the hypothesis that multiple immunizations increase the risk for immune dysfunction and found that the epidemiological evidence favors rejection of a causal relationship between multiple immunization and increased risk for infections and for type 1 diabetes.

Safety of Vaccines Used for Routine Immunization in the United States.

Evidence was insufficient to make conclusions regarding whether several routinely recommended vaccines are associated with serious conditions such as multiple sclerosis, transverse myelitis, and acute disseminated encephalomyelitis; however, important factors must be taken into account when determining whether studies are warranted.

Adverse Effects of Vaccines

While no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines, and the evidence shows that vaccines do not cause several conditions.

Vaccine administration and the development of immune thrombocytopenic purpura in children

The available data clearly indicate that ITP is very rare and the only vaccine for which there is a demonstrated cause-effect relationship is the measles, mumps and rubella vaccine that can occur in 1 to 3 children every 100,000 vaccine doses.
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