The state of the art of in vitro fertilization.

  title={The state of the art of in vitro fertilization.},
  author={Adam J. Fechner and Peter G McGovern},
  journal={Frontiers in bioscience},
Since the first description of successful human in vitro fertilization in 1978, researchers and clinicians have been striving to improve the efficacy and safety of the technique. Advances in technology and in our understanding of human reproduction have contributed to increased success rates and decreased rates of higher order multiple births. However, there is still room for improvement as 'unexplained infertility' still affects many couples, and the incidence of twin pregnancies remains… 

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