The state of lipid rafts: from model membranes to cells.

@article{Edidin2003TheSO,
  title={The state of lipid rafts: from model membranes to cells.},
  author={Michael A. Edidin},
  journal={Annual review of biophysics and biomolecular structure},
  year={2003},
  volume={32},
  pages={
          257-83
        }
}
Lipid raft microdomains were conceived as part of a mechanism for the intracellular trafficking of lipids and lipid-anchored proteins. The raft hypothesis is based on the behavior of defined lipid mixtures in liposomes and other model membranes. Experiments in these well-characterized systems led to operational definitions for lipid rafts in cell membranes. These definitions, detergent solubility to define components of rafts, and sensitivity to cholesterol deprivation to define raft functions… CONTINUE READING

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References

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Lipid polarity and sorting in epithelial cells.

  • Journal of cellular biochemistry
  • 1988
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Lipid sorting in epithelial cells.

  • Biochemistry
  • 1988
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HIGHLY INFLUENTIAL

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