The standard strong ion difference, standard total titratable base, and their relationship to the Boston compensation rules and the Van Slyke equation for extracellular fluid

@article{Wooten2010TheSS,
  title={The standard strong ion difference, standard total titratable base, and their relationship to the Boston compensation rules and the Van Slyke equation for extracellular fluid},
  author={DPhil E. Wrenn Wooten},
  journal={Journal of Clinical Monitoring and Computing},
  year={2010},
  volume={24},
  pages={177-188}
}
A general formalism for calculating physiological acid–base balance in multiple compartments is extended to the combined interstitial, plasma, and erythrocyte multicompartment system in humans using the Siggaard-Andersen approximation for interstitial fluid. The resulting equations for total titratable base and strong ion difference reproduce the experimental in vivo carbon dioxide titration curve as well as the experimental strong ion difference value of the interstitial, plasma, and… CONTINUE READING
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Textbook of medical physiology

  • AC Guyton, JE Hall
  • (11th ed.). Elsevier, Inc.: Philadelphia,
  • 2006
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