The stability of the nitrosated products of indole, indole-3-acetonitrile, indole-3-carbinol and 4-chloroindole.

@article{Tiedink1989TheSO,
  title={The stability of the nitrosated products of indole, indole-3-acetonitrile, indole-3-carbinol and 4-chloroindole.},
  author={Henrika G. M. Tiedink and Julian A. Davies and Nora A. Visser and Wim M. F. Jongen and L W van Broekhoven},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={1989},
  volume={27 11},
  pages={723-30}
}
The nitrosation rates of indole-3-acetonitrile, indole-3-carbinol, indole and 4-chloroindole and the stability of their nitrosated products were investigated. Each of the nitrosated indole compounds was directly mutagenic to Salmonella typhimurium TA100 in the following order of potency: 4-chloroindole much greater than indole-3-carbinol greater than or equal to indole greater than indole-3-acetonitrile. Total N-nitroso determinations, carried out according to a modified method of Walters et al… CONTINUE READING