The stability and in vitro release kinetics of a clofibride emulsion

@inproceedings{Magalhaes1991TheSA,
  title={The stability and in vitro release kinetics of a clofibride emulsion},
  author={N.S.Santos Magalhaes and G. Delle Cave and Monique Seiller and Shimon Benita},
  year={1991}
}
Abstract Soybean and MCT submicron emulsions of clofibride were prepared using an optimal combination of phosphatidylcholine to poloxamer (molar ratio of 1:1). Both emulsions exhibited a mean droplet size in the range of 100–150 nm, and displayed identical Newtonian rheological behavior. The results of the accelerated stability tests indicated that the soybean emulsion was more resistant to various mechanical and thermal stresses than the MCT emulsion. The soybean emulsion remained stable even… CONTINUE READING