The squamous cell carcinoma antigens as relevant biomarkers of atopic dermatitis.

@article{Mitsuishi2005TheSC,
  title={The squamous cell carcinoma antigens as relevant biomarkers of atopic dermatitis.},
  author={Kouichi Mitsuishi and Takanori Nakamura and Yasuhisa Sakata and Noriko Yuyama and Kazuhiko Arima and Yuji Sugita and Hajime Suto and Kenji Izuhara and Hideoki Ogawa},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2005},
  volume={35 10},
  pages={1327-33}
}
BACKGROUND Although it is thought that both Th1- and Th2-type inflammations are involved in the pathogenesis of atopic dermatitis (AD), it is controversial which immune response is more involved in regulating the clinical severity of AD. We recently found that the squamous cell carcinoma antigens 1 (SCCA1) and SCCA2 are novel biomarkers of bronchial asthma, downstream of IL-4 and IL-13. OBJECTIVE We examined whether SCCA1 and SCCA2 could also serve as biomarkers of AD, reflecting its Th2-type… CONTINUE READING
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