The spread of the Leu-Phe kdr mutation through Anopheles gambiae complex in Burkina Faso: genetic introgression and de novo phenomena.

@article{Diabat2004TheSO,
  title={The spread of the Leu-Phe kdr mutation through Anopheles gambiae complex in Burkina Faso: genetic introgression and de novo phenomena.},
  author={Abdoulaye Diabat{\'e} and C{\'e}cile Brengues and Thierry Baldet and Kounbobr R Dabir{\'e} and Jean Marc Hougard and Martin C. Akogb{\'e}to and Pierre Kengne and Fr{\'e}d{\'e}ric Simard and Pierre F. Guillet and Janet Hemingway and Fabrice Chandre},
  journal={Tropical medicine & international health : TM & IH},
  year={2004},
  volume={9 12},
  pages={
          1267-73
        }
}
During extensive sampling in Burkina Faso and other African countries, the Leu-Phe mutation producing the kdr pyrethroid resistance phenotype was reported in both Anopheles gambiae ss and A. arabiensis. This mutation was widely distributed at high frequency in the molecular S form of A. gambiae while it has been observed at a very low frequency in both the molecular M form and A. arabiensis in Burkina Faso. While the mutation in the M form is inherited through an introgression from the S form… CONTINUE READING
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