The spread of neurodegenerative disease.

@article{Hardy2012TheSO,
  title={The spread of neurodegenerative disease.},
  author={John Hardy and Tamas R Revesz},
  journal={The New England journal of medicine},
  year={2012},
  volume={366 22},
  pages={2126-8}
}
Clinicians who care for patients with neurodegenerative disease often believe that their patients’ diseases are spreading through their brains. Braak’s anatomical staging of Alzheimer’s disease and Parkinson’s disease reflects the view that the pathologic features of these diseases spread. Of course, clinical impressions and the distinctive anatomy of these diseases could be explained in many ways. They could result from selective vulnerability in the face of increasing external metabolic… CONTINUE READING
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