The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study

@inproceedings{Imwong2017TheSO,
  title={The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study},
  author={Mallika Imwong and Kanokon Suwannasin and Chanon Kunasol and Kreepol Sutawong and Mayfong Mayxay and Huy Rekol and Frank M. Smithuis and Tin Maung Hlaing and Kyaw Myo Tun and Rob W. van der Pluijm and Rupam Tripura and Olivo Miotto and Didier M{\'e}nard and Mehul Dhorda and Nicholas P J Day and Nicholas J White and Arjen Mattheus Dondorp},
  booktitle={The Lancet. Infectious diseases},
  year={2017}
}
BACKGROUND Evidence suggests that the PfKelch13 mutations that confer artemisinin resistance in falciparum malaria have multiple independent origins across the Greater Mekong subregion, which has motivated a regional malaria elimination agenda. We aimed to use molecular genotyping to assess antimalarial drug resistance selection and spread in the Greater Mekong subregion. METHODS In this observational study, we tested Plasmodium falciparum isolates from Myanmar, northeastern Thailand… CONTINUE READING
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