The splenic syndrome in individuals with sickle cell trait.

  title={The splenic syndrome in individuals with sickle cell trait.},
  author={Jessica Goodman and Kathryn Hassell and David C Irwin and Ewa H Witkowski and Rachelle Nuss},
  journal={High altitude medicine & biology},
  volume={15 4},
The medical records of 25 individuals with sickle cell trait and altitude-associated splenic infarct, reported to two Colorado physicians, were reviewed. Electrospray mass spectroscopy was performed on blood samples from a cohort of 10 of the individuals to rapidly confirm beta hemoglobin phenotype. Only males were identified with a 1.4:1 ratio of non-African Americans to African Americans, and 44% of African Americans and 85% of non-African Americans were unaware they had sickle cell trait… CONTINUE READING
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