The speed of change: towards a discontinuity theory of immunity?

@article{Pradeu2013TheSO,
  title={The speed of change: towards a discontinuity theory of immunity?},
  author={Thomas Pradeu and S{\'e}bastien Jaeger and {\'E}ric Vivier},
  journal={Nature Reviews Immunology},
  year={2013},
  volume={13},
  pages={764-769}
}
Immunology — though deeply experimental in everyday practice — is also a theoretical discipline. Recent advances in the understanding of innate immunity, how it is triggered and how it shares features that have previously been uniquely ascribed to the adaptive immune system, can contribute to the refinement of the theoretical framework of immunology. In particular, natural killer cells and macrophages are activated by transient modifications, but adapt to long-lasting modifications that occur… 

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