The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome.

@article{Vincent1992TheSO,
  title={The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome.},
  author={G. Michael Vincent and Katherine W. Timothy and M. Leppert and Mark T. Keating},
  journal={The New England journal of medicine},
  year={1992},
  volume={327 12},
  pages={846-52}
}
BACKGROUND The familial long-QT syndrome is characterized by a prolonged QT interval on the electrocardiogram, ventricular arrhythmias, and sudden death. It is not certain, however, that the length of the QT interval is a sensitive or a specific diagnostic criterion. Recently, we identified genetic markers on chromosome 11 that distinguished between carriers and noncarriers of the gene for the long-QT syndrome in three families. In this study, we compared the clinical features of carriers and… CONTINUE READING
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