The spectrum of celiac disease: epidemiology, clinical aspects and treatment

  title={The spectrum of celiac disease: epidemiology, clinical aspects and treatment},
  author={G. J. Tack and W. Verbeek and M. Schreurs and C. Mulder},
  journal={Nature Reviews Gastroenterology &Hepatology},
  • G. J. Tack, W. Verbeek, +1 author C. Mulder
  • Published 2010
  • Medicine
  • Nature Reviews Gastroenterology &Hepatology
  • Celiac disease is a gluten-sensitive enteropathy that affects people of all ages worldwide. This disease has emerged as a major health-care problem, as advances in diagnostic and screening methods have revealed its global prevalence. Environmental factors such as gluten introduction at childhood, infectious agents and socioeconomic features, as well as the presence of HLA-DQ2 and/or HLA-DQ8 haplotypes or genetic variations in several non-HLA genes contribute to the development of celiac disease… CONTINUE READING
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