The spectrum of MOG autoantibody-associated demyelinating diseases

@article{Reindl2013TheSO,
  title={The spectrum of MOG autoantibody-associated demyelinating diseases},
  author={Markus Reindl and Franziska Di Pauli and Kevin Rost{\'a}sy and Thomas Berger},
  journal={Nature Reviews Neurology},
  year={2013},
  volume={9},
  pages={455-461}
}
Myelin oligodendrocyte glycoprotein (MOG) has been identified as a target of demyelinating autoantibodies in animal models of inflammatory demyelinating diseases of the CNS, such as multiple sclerosis (MS). Numerous studies have aimed to establish a role for MOG antibodies in patients with MS, although the results have been controversial. Cell-based immunoassays using MOG expressed in mammalian cells have demonstrated the presence of high-titre MOG antibodies in paediatric patients with acute… 
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