The spectra of neurasthenia and depression: course, stability and transitions

  title={The spectra of neurasthenia and depression: course, stability and transitions},
  author={Alex Gamma and Jules Angst and Vladeta Ajdacic and Dominique Eich and Wulf R{\"o}ssler},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
  • A. Gamma, J. Angst, W. Rössler
  • Published 1 March 2007
  • Psychology, Medicine
  • European Archives of Psychiatry and Clinical Neuroscience
BackgroundNeurasthenia has had a chequered history, receiving changing labels such as chronic fatigue or Gulf war syndrome. Neurasthenia is recognized by ICD-10, but not by DSM-IV. Its course, longitudinal stability and relationship to depression is not well understood.MethodsIn a stratified community sample (n = 591), representative of 2600 persons of the canton of Zurich, Switzerland, neurasthenia and depression were assessed in six structured interviews between ages 20 and 41. Course… 
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