The specificity of the binding site of AchatininH, a sialic acid-binding lectin from Achatina fulica.

  title={The specificity of the binding site of AchatininH, a sialic acid-binding lectin from Achatina fulica.},
  author={G. Sen and C. Mandal},
  journal={Carbohydrate research},
  volume={268 1},
  • G. Sen, C. Mandal
  • Published 1995
  • Chemistry, Medicine
  • Carbohydrate research
  • A sialic acid-binding lectin, AchatininH (ATNH), having unique specificity towards 9-O-acetylneuraminic acid, has been purified and characterized. The specificity of this lectin for O-acetylsialic acids was studied in detail, using various sialic acid derivatives and sialoglycoproteins. The potent inhibition of hemagglutination by bovine submaxillary mucin (BSM), which contains 9(7,8)-O-acetylsialic acid and by free 9-O-acetylneuraminic acid confirms the preferential affinity towards this sugar… CONTINUE READING
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