The specific fates of tight junction proteins in apoptotic epithelial cells.

@article{Bojarski2004TheSF,
  title={The specific fates of tight junction proteins in apoptotic epithelial cells.},
  author={Christian Bojarski and Joerg Weiske and Torsten Sch{\"o}neberg and Werner F. K. J. Schr{\"o}der and Joachim Mankertz and J. -D. Schulzke and Peter Florian and Michael Fromm and Rudolf Tauber and Otmar Huber},
  journal={Journal of cell science},
  year={2004},
  volume={117 Pt 10},
  pages={2097-107}
}
The polarized morphology of epithelial cells depends on the establishment and maintenance of characteristic intercellular junctions. The dramatic morphological changes observed in apoptotic epithelial cells were ascribed at least in part to the specific fragmentation of components of adherens junctions and desmosomes. Little, however, is known about tight junctions during apoptosis. We have found that after induction of apoptosis in epithelial cells, tight junction proteins undergo proteolytic… CONTINUE READING
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