The specific binding of estradiol to the nuclear matrix.

  title={The specific binding of estradiol to the nuclear matrix.},
  author={Evelyn R. Barrack and E. F. Hawkins and D S Coffey},
  journal={Advances in experimental medicine and biology},
Recent studies on the eukaryotic nucleus have described the presence of a structural component termed the nuclear matrix, that appears to be involved in nucleic acid synthesis. This study will present evidence that the nuclear matrix of both the rat uterus and chick liver contains specific, high affinity, saturable estradiol binding sites. 

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