The spatial learning phenotype of heterozygous leaner mice is robust to systematic variation of the housing environment.

Abstract

Providing stimulation and allowing the performance of motivated behaviors through environmental enrichment improves learning and memory in rodents and delays cognitive impairment in neurodegenerative disease models. The leaner mutation affects the Ca(v)2.1 voltage-gated calcium channel alpha(1A)-subunit gene, and homozygous mice show severe phenotypic… (More)

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@article{Marques2009TheSL, title={The spatial learning phenotype of heterozygous leaner mice is robust to systematic variation of the housing environment.}, author={Joana Moreira Marques and Isabel Alonso and Cristina Santos and Isabel Silveira and I. Anna S. Olsson}, journal={Comparative medicine}, year={2009}, volume={59 2}, pages={129-38} }