The spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements.

@article{Basler1989TheSA,
  title={The spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements.},
  author={Konrad Basler and Philip Siegrist and Ernst Hafen},
  journal={The EMBO journal},
  year={1989},
  volume={8 8},
  pages={2381-6}
}
The sevenless gene controls the fate of a single photoreceptor cell type in the developing eye of Drosophila. Its RNA and protein accumulate transiently in a subpopulation of cells in the developing eye imaginal disc. We have used P-element transformation with different minigenes and marker gene constructs to identify cis-acting regulatory regions required for the complex sevenless expression pattern. Our results indicate that the upstream region of the sevenless gene is devoid of any… CONTINUE READING

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