The sortase SrtA of Listeria monocytogenes is involved in processing of internalin and in virulence.

@article{Garandeau2002TheSS,
  title={The sortase SrtA of Listeria monocytogenes is involved in processing of internalin and in virulence.},
  author={Caroline Garandeau and H{\'e}l{\`e}ne R{\'e}glier-Poupet and Iharilalao Dubail and J Beretti and Patrick Berche and Alain Charbit},
  journal={Infection and immunity},
  year={2002},
  volume={70 3},
  pages={1382-90}
}
Listeria monocytogenes is an intracellular gram-positive human pathogen that invades eucaryotic cells. Among the surface-exposed proteins playing a role in this invasive process, internalin belongs to the family of LPXTG proteins, which are known to be covalently linked to the bacterial cell wall in gram-positive bacteria. Recently, it has been shown in Staphylococcus aureus that the covalent anchoring of protein A, a typical LPXTG protein, is due to a cysteine protease, named sortase, required… CONTINUE READING

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