The solid-state cultivation of Streptococcus zooepidemicus in polyurethane foam as a strategy for the production of hyaluronic acid.

Abstract

Hyaluronic acid (HA) is a biopolymer with important applications in the pharmaceutical, medical, and cosmetic fields. This work explores the potentialities of a cylindrical polyurethane foam dowel with central aeration as a novel packed bed bioreactor for the production of HA. The goals were to provide a large surface area for oxygen transfer through the… (More)
DOI: 10.1007/s12010-013-0293-0

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