The soil resistome: a critical review on antibiotic resistance origins, ecology and dissemination potential in telluric bacteria.

@article{Nesme2015TheSR,
  title={The soil resistome: a critical review on antibiotic resistance origins, ecology and dissemination potential in telluric bacteria.},
  author={Joseph Nesme and Pascal Simonet},
  journal={Environmental microbiology},
  year={2015},
  volume={17 4},
  pages={
          913-30
        }
}
Soil is a large reservoir of microbial diversity and the majority of antimicrobial compounds used today in human and veterinary health care have been isolated from soil microorganisms. The Darwinian hypothesis of an 'arms-shields race' between antibiotic producers and resistant strains is often cited to explain antibiotic resistance gene determinants (ARGD) origins and diversity. ARGD abundance and antibiotic molecule exposure are, however, not systematically linked, and many other factors can… CONTINUE READING
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