The sodium-dependent glucose cotransporter SLC5A11 as an autoimmune modifier gene in SLE.

@article{Tsai2008TheSG,
  title={The sodium-dependent glucose cotransporter SLC5A11 as an autoimmune modifier gene in SLE.},
  author={Li-ming Tsai and S-H Hsiao and L-M Tsai and C-Y Lin and J-J Tsai and D Y Liou and J Lan},
  journal={Tissue antigens},
  year={2008},
  volume={71 2},
  pages={114-26}
}
Genetic studies in several human autoimmune diseases suggest that the pericentromeric region of chromosome 16 might harbor an autoimmune modifier gene. We hypothesized that the sodium-dependent glucose cotransporter gene SLC5A11 is such a gene, and so might interact with immune-related genes. Herein, this hypothesis was tested in a genetic evaluation of the multiple gene effect in systemic lupus erythematosus (SLE). We used the case-control candidate gene association approach. Eight immune… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…