The smallest unit: effector and memory CD8+ T cell differentiation on the single cell level

@inproceedings{Buchholz2013TheSU,
  title={The smallest unit: effector and memory CD8+ T cell differentiation on the single cell level},
  author={Veit R. Buchholz and Patricia Graef and Dirk H Busch},
  booktitle={Front. Immun.},
  year={2013}
}
CD8(+) T cell immune responses provide immediate protection against primary infection and durable memory capable of rapidly fighting off re-infection. Immediate protection and lasting memory are implemented by phenotypically and functionally distinct T cell subsets. While it is now widely accepted that these diverge from a common source of naïve T cells (T(n)), the developmental relation and succession of effector and memory T cell subsets is still under intense debate. Recently, a distinct… CONTINUE READING
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