The smallest genome RNA segment of influenza virus contains two genes that may overlap.

@article{Inglis1979TheSG,
  title={The smallest genome RNA segment of influenza virus contains two genes that may overlap.},
  author={Stephen C. Inglis and T. K. Barrett and Charlie M. Brown and Jeffrey W. Almond},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1979},
  volume={76 8},
  pages={3790-4}
}
The genome of influenza virus consists of eight segments of single-stranded RNA, each of which encodes a different polypeptide. In addition to the eight recognized gene products, the virus specifies a distinct smaller nonstructural polypeptide (NS2), which is translated from a separate species of virus-specific mRNA. The location on the virus genome of the gene encoding this polypeptide was investigated by hybridization of the NS2 mRNA with isolated subgenomic RNA species, and by correlation of… CONTINUE READING

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