The small-subunit processome is a ribosome assembly intermediate.

@article{Bernstein2004TheSP,
  title={The small-subunit processome is a ribosome assembly intermediate.},
  author={Kara A Bernstein and Jennifer E. G. Gallagher and Brianna M. Mitchell and Sander Granneman and Susan J Baserga},
  journal={Eukaryotic cell},
  year={2004},
  volume={3 6},
  pages={
          1619-26
        }
}
The small-subunit (SSU) processome is a large ribonucleoprotein required for the biogenesis of the 18S rRNA and likely corresponds to the terminal knobs visualized by electron microscopy on the 5' end of nascent rRNAs. The original purification of the SSU processome of Saccharomyces cerevisiae resulted in the identification of 28 proteins. Here, we characterize 12 additional protein components, including five small-ribosomal-subunit proteins (Rps4, Rps6, Rps7, Rps9, and Rps14) that had… CONTINUE READING

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