The small intestine plays an important role in upregulating CGRP during sepsis.

@article{Zhou2001TheSI,
  title={The small intestine plays an important role in upregulating CGRP during sepsis.},
  author={Mian Zhou and Antony J Arthur and Zheng F. Ba and Irshad H. Chaudry and Ping Wang},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2001},
  volume={280 2},
  pages={R382-8}
}
Although studies have indicated that calcitonin gene-related peptide (CGRP), a potent vasodilatory peptide, is upregulated after endotoxic shock, it remains controversial whether this peptide increases during sepsis and, if so, whether the gut is a significant source of CGRP under such conditions. To study this, polymicrobial sepsis was induced by cecal ligation and puncture (CLP) followed by fluid resuscitation. Plasma levels of CGRP were measured at 2, 5, and 10 h after CLP (i.e., early… CONTINUE READING

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