The small interferon-induced transmembrane genes and proteins.

@article{Siegrist2011TheSI,
  title={The small interferon-induced transmembrane genes and proteins.},
  author={F. Siegrist and M. Ebeling and U. Certa},
  journal={Journal of interferon \& cytokine research : the official journal of the International Society for Interferon and Cytokine Research},
  year={2011},
  volume={31 1},
  pages={
          183-97
        }
}
  • F. Siegrist, M. Ebeling, U. Certa
  • Published 2011
  • Biology, Medicine
  • Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Interferon-induced transmembrane (IFITM) genes are transcribed in most tissues and are with the exception of IFITM5 interferon inducible. They are involved in early development, cell adhesion, and control of cell growth. Most IFITM genes are activated in response to bacterial and viral infections, and the exact host immune defense mechanisms are still unknown. Elevated gene expression triggered by past or chronic inflammation could prevent spreading of pathogens by limiting host cell… Expand
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