The small colony variant (SCV) concept -- the role of staphylococcal SCVs in persistent infections.

@article{Eiff2006TheSC,
  title={The small colony variant (SCV) concept -- the role of staphylococcal SCVs in persistent infections.},
  author={Christof von Eiff and Georg Peters and Karsten Becker},
  journal={Injury},
  year={2006},
  volume={37 Suppl 2},
  pages={S26-33}
}
The recovery of small colony variants (SCVs) from clinical specimens was first described at the beginning of the last century. However, not until the past decade was an association of these variants with chronic, recurrent, and persistent infections such as chronic osteomyelitis and persistent skin and softtissue infection described. Since then, a number of reports and prospective studies have supported a pathogenic role for SCVs in disease. Biochemical and other characteristics of SCVs have… CONTINUE READING
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