The small co-chaperone p23 overexpressing transgenic mouse.

Abstract

Studies from multiple laboratories have identified the roles of several ER stress-induced cell death modulators and effectors. Earlier, we described the role of p23 a small co-chaperone protein in preventing ER stress-induced cell death. p23 is cleaved by caspases at D142 to yield p19 (a 19 kDa product) during ER stress-induced cell death. Mutation of the… (More)
DOI: 10.1016/j.jneumeth.2012.09.022

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