The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans

@article{KageNakadai2018TheSG,
  title={The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans},
  author={Eriko Kage-Nakadai and Simo Sun and Satoru Iwata and Sawako Yoshina and Yoshikazu Nishikawa and Shohei Mitani},
  journal={The Journal of Physiological Sciences},
  year={2018},
  pages={1-10}
}
The membrane trafficking events that regulate unicellular tube formation and maintenance are not well understood. Here, using an RNAi screen, we identified the small GTPase ARF1 homolog ARF-1.2 as a regulator of excretory tube formation in Caenorhabditis elegans. RNAi-mediated knockdown and knockout of the arf-1.2 gene resulted in the formation of large… CONTINUE READING