The sleep therapies of depression

  title={The sleep therapies of depression},
  author={J. Christian Gillin},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
This paper reviews five different types of deliberate sleep-wake manipulations which are reported to have antidepressant effects: total sleep deprivation, partial sleep deprivation, a phase advance of the sleep periods, and REM deprivation. The effects of total sleep deprivation are best documented. Of 852 depressed patients studied, 493 or 57.9% improved following sleep deprivation. The REM deprivation procedure acts more slowly, but is of more lasting clinical value than the other forms… CONTINUE READING

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