The skin immune system and the challenge of tumour immunosurveillance.

@article{Woods2005TheSI,
  title={The skin immune system and the challenge of tumour immunosurveillance.},
  author={Gregory J. M. Woods and Roslyn C. Malley and Hans Konrad Muller},
  journal={European journal of dermatology : EJD},
  year={2005},
  volume={15 2},
  pages={
          63-9
        }
}
The Skin Immune System (SIS) is a relatively new concept central to the issue of cutaneous tumour surveillance. The Langerhans cell (LC) is a key component of SIS. Skin cancer causing agents such as ultraviolet B (UV-B) irradiation and chemical carcinogens like dimethylbenz(a)anthracene (DMBA) alter LC function, resulting in immunosuppression and the promotional phase of tumour development. Once tumours, such as melanoma, are established they may show evidence of tumour regression due to immune… CONTINUE READING
Highly Cited
This paper has 38 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 20 CITATIONS

Similar Papers

Loading similar papers…